The proteins thymosin and profilin prevent the spontaneous nucleation of new actin trimers.
2.
Hence, the oversaturation must be several times higher than the normal saturation value for spontaneous nucleation to occur.
3.
It is unlikely, however, that new phases often arise by this fluctuation mechanism and the resultant spontaneous nucleation.
4.
Any contact between fluid and the surface that may be seen probably leads to the extremely rapid nucleation of a fresh vapor layer ( " spontaneous nucleation " ).
5.
Thymosin and Profilin both exist as actin-monomer-sequestering proteins that maintain the ability to limit spontaneous nucleation from occurring, thus halting the actin remodeling process and returning the cycle to its first step.
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